Skin Indications (Pt 1) : Sensitive Skin

Part 1 : Sensitive Skin

Sensitivity is an inherited or acquired condition caused by genetics and environmental stressors that cause ongoing trauma to the skin.

SYMPTOMS

  • Redness and inflammation
  • Temperature sensitivity
  • Sunburns easily
  • Blushing when hot, angry, consuming alcoholic beverages, exercising, or eating spicy foods
  • Irritation to cosmetics
  • Blotching
  • Prone to breakouts
  • Prone to rashes
  • Thin, fragile, and/or healing skin

CAUSES

Inherited Sensitization

Sensitive skin can result from a complex interplay of biochemical pathways and factors, making it challenging to pinpoint a culprit.  Effective management requires a multifaceted approach that addresses barrier function, inflammation, and triggers specific to the individual’s skin type and sensitivities. However, several key biochemical pathways commonly associated with sensitive skin are:

  • Rosacea, psoriasis, and eczema
  • Seborrheic dermatitis
  • Atopic dermatitis
  • Contact dermatitis

Acquired Sensitization

  • Allergies
  • Sun, wind, cold, pollution
  • Preservatives and fragrance
  • Clinical or aesthetic procedures
  • Skincare products that contain salicylic acid, retinoids, alcohol, fragrances, parabens, and sodium lauryl sulfate.

Other influencing factors:

  • Skin Barrier Function: Ceramide, fatty acid, or cholesterol deficiencies disrupt the skin barrier ’s function. This allows irritants, allergens, and pathogens to penetrate the skin more easily, triggering inflammation and discomfort.
  • Neurogenic Inflammation: Nerve endings in the skin become overly responsive, leading to sensations of itching, burning, or stinging. Neurotransmitter-like substances can influence neurogenic inflammation.Neurotransmitters like substance P can influence neurogenic inflammation.
  • Immune Response: Inflammatory cytokines, such as interleukins, can cause an exaggerated immune response, particularly in individuals with conditions like rosacea or eczema.
  • Oxidative Stress: Exposure to environmental stressors influences the balance between free radicals and antioxidants in the skin, which contributes to sensitivit y and inflammation.
  • Neurotransmitters: Neurotransmitters like histamine and acetylcholine activate skin cell receptors, causing hypersensitivity.
  • Innate Immunity: Toll-like receptors (TLRs) and other components of the skin’s innate immune system sense and respond to external irritants and allergens.